The situation, in line with the Stiff Individual Syndrome Basis, impacts the central nervous system, particularly the mind and spinal wire. “Sufferers might be disabled, wheelchair-bound or bed-ridden, unable to work and take care of themselves,” they are saying, including that the neurological illness with autoimmune options can embrace signs like “hyper-rigidity, debilitating ache, power nervousness,” and muscle spasms “so violent they’ll dislocate joints and even break bones.”